Pubs
Recent Publications
Reindl W, Bowen BP, Balamotis MA, Green JE, Northen TR: Multivariate analysis of a 3D mass spectral image for examining tissue heterogeneity. Integr Biol (Camb) 2011.
Lopes LB, Brophy CM, Flynn CR, Yi Z, Bowen BP, Smoke C, Seal B, Panitch A, Komalavilas P: A novel cell permeant peptide inhibitor of MAPKAP kinase II inhibits intimal hyperplasia in a human saphenous vein organ culture model. J Vasc Surg 2010, 52(6):1596-1607.
Lefort N, Glancy B, Bowen B, Willis WT, Bailowitz Z, De Filippis EA, Brophy C, Meyer C, Hojlund K, Yi Z et al: Increased reactive oxygen species production and lower abundance of complex I subunits and carnitine palmitoyltransferase 1B protein despite normal mitochondrial respiration in insulin-resistant human skeletal muscle. Diabetes 2010, 59(10):2444-2452.
Wilmes, Paul ; Bowen, Benjamin P ; Thomas Brian C; Mueller Ryan S; Denef Vincent J; VerBerkmoes Nathan C; Hettich Robert L; Northen Trent R; and Banfield Jillian F. Metabolome-proteome differentiation coupled to microbial divergence. mBio (in Press).
Facciotti M.T., Pang W.L., Lo F-Y., Whitehead K., Koide T., Masumura K., Pan M., Kaur A., Larsen D.J., Reiss D.J., Hoang L., Kalisiak E., Northen T., Trauger S.A., Siuzdak G., Baliga N.S. Large scale physiological readjustment during growth enables rapid, comprehensive and inexpensive system analysis. BMC Systems Biology 4:64 (2010)
Baran R, Bowen BP, Bouskill NJ, Brodie EL, Yannone SM, Northen TR (2010) Metabolite Identification in Synechococcus sp. PCC 7002 Using Untargeted Stable Isotope Assisted Metabolite Profiling. Analytical Chemistry 82(21): 9034–9042
Lee, Do Yup, Bowen, Benjamin P, Northen, Trent R. Mass spectrometry based metabolomics, analysis of metabolite-protein interactions, and imaging. Biotechniques, (2010), 49(2): 557-65 (COVER).
Hwang H, Bowen BP, Lefort N, Flynn CR, De Filippis EA, Roberts C, Smoke CC, Meyer C, Hojlund K, Yi Z et al: Proteomics Analysis of Human Skeletal Muscle Reveals Novel Abnormalities in Obesity and Type 2 Diabetes. Diabetes 2010, 59(1):33-42.
Lefort N, Glancy B, Bowen B, Willis WT, Bailowitz Z, De Filippis EA, Brophy C, Meyer C, Hojlund K, Yi ZP et al: Increased Reactive Oxygen Species Production and Lower Abundance of Complex I Subunits and Carnitine Palmitoyltransferase 1B Protein Despite Normal Mitochondrial Respiration in Insulin-Resistant Human Skeletal Muscle. Diabetes 2010, 59(10):2444-2452.
Hojlund K, Yi Z, Lefort N, Langlais P, Bowen B, Levin K, Beck-Nielsen H, Mandarino LJ: Human ATP synthase beta is phosphorylated at multiple sites and shows abnormal phosphorylation at specific sites in insulin-resistant muscle. Diabetologia 2010, 53(3):541-551.
Xie XT, Yi ZP, Bowen B, Wolf C, Flynn CR, Sinha S, Mandarino LJ, Meyer C: Characterization of the Human Adipocyte Proteome and Reproducibility of Protein Abundance by One-Dimensional Gel Electrophoresis and HPLC-ESI-MS/MS. Journal of Proteome Research 2010, 9(9):4521-4534.
Bowen, Benjamin P., Northen, Trent. Dealing with the unknown: Metabolomics and Metabolite Atlases, JASMS (2010). 21(9):1471-1476.
Jansson, Christer, Northen, Trent. Calcifying cyanobacteria-the potential of biomineralization for carbon capture and storage. curr opin biotechnol (2010) 2010 Jun;21(3):365-71
Reindl, Wolfgang; Northen, Trent. Rapid Screening of Fatty Acids Using Nanostructure-Initiator Mass Spectrometry. Analytical Chemistry (2010), 9, 3751-3755.
Baran, Richard; Reindl, Wolfgang; Northen, Trent. Mass Spectrometry Based Metabolomics and Enzymatic Assays for Functional Genomics. Current Op. in Microbiology (2009), 12, 547-552 COVER.
Woo, Hin-Koon; Go, Eden P; Hoang, Linh; Trauger, Sunia A.; Bowen, Benjamin; Siuzdak, Gary; Northen, Trent R.. Phosphonium Labeling for Increasing Metabolomic Coverage of Neutral Lipids using ESI-MS. Rapid. Comm. Mass Spec. (2009) 23(12), 1849-55.
Brower JB, Targovnik JH, Bowen BP, Caplan MR, Massia SP: Elevated Glucose Impairs the Endothelial Cell Response to Shear Stress. Cellular and Molecular Bioengineering 2009, 2(4):533-543.
Lefort N, Yi Z, Bowen B, Glancy B, De Filippis EA, Mapes R, Hwang H, Flynn CR, Willis WT, Civitarese A et al: Proteome profile of functional mitochondria from human skeletal muscle using one-dimensional gel electrophoresis and HPLC-ESI-MS/MS. J Proteomics 2009, 72(6):1046-1060.
Hojlund K, Bowen BP, Hwang H, Flynn CR, Madireddy L, Geetha T, Langlais P, Meyer C, Mandarino LJ, Yi ZP: In vivo Phosphoproteome of Human Skeletal Muscle Revealed by Phosphopeptide Enrichment and HPLC-ESI-MS/MS. Journal of Proteome Research 2009, 8(11):4954-4965.
Northen Trent R, Lee J-C, Hoang L., Raymond J., Hwang D-R, Yannone S.M., Wong C-H, Siuzdak G. A Nanostructure-Initiator Mass Spectrometry Based Enzyme Activity Assay, PNAS, (2008)105(10), 3678-3683.
Northen T.R. Greving M., Woodbury N.W. Combinatorial Screening of Biomimetic Protein Affinity Materials. Advanced Materials (2008) 20, 1-7.
Yi ZP, Bowen BP, Hwang H, Jenkinson CP, Coletta DK, Lefort N, Bajaj M, Kashyap S, Berria R, De Filippis EA et al: Global relationship between the proteome and transcriptome of human skeletal muscle. Journal of Proteome Research 2008, 7(8):3230-3241.
Hojlund K, Yi ZP, Hwang H, Bowen B, Lefort N, Flynn CR, Langlais P, Weintraub ST, Mandarino LJ: Characterization of the human skeletal muscle proteome by one-dimensional gel electrophoresis and HPLC-ESI-MS/MS. Molecular & Cellular Proteomics 2008, 7(2):257-267.
Woo H-K., Northen T.R., Yanes O., Siuzdak G. Nanostructure-Initiator Mass Spectrometry (NIMS): A protocol for preparing and applying NIMS surfaces for high sensitivity mass analysis.Nature Protocols 3, 1341-1349 (2008)
Northen, Trent R; Wu, Hin-Koon, Northen, Michael T; Nordström, Anders; Uritboonthai, Winnie; Turner, Kimberly L., Sizudak, Gary. High Surface Energy of Porous Silicon Drives Desorption of Intact Molecules. JASMS (2007) 18 (11), 1945-1949.
Northen, Trent R; Yanes, Oscar; Northen, Michael T; Marrinucci, Dena C; Uritboonthai, Winnie; Apon, Junefredo ; Golledge, Stephen L; Nordström, Anders; Sizudak, Gary. Clathrate Nanostructures for Mass Spectrometry. Nature (2007) 449, 1033-1036.
Bowen BP, Scruggs A, Enderlein J, Sauer M, Woodbury N: Implementation of neural networks for the identification of single molecules. Journal of Physical Chemistry A 2004, 108(21):4799-4804.
Haffa ALM, Lin S, Williams JC, Bowen BP, Taguchi AKW, Allen JP, Woodbury NW: Controlling the pathway of photosynthetic charge separation in bacterial reaction centers. Journal of Physical Chemistry B 2004, 108(1):4-7.
Montano GA, Bowen BP, LaBelle JT, Woodbury NW, Pizziconi VB, Blankenship RE: Characterization of Chlorobium tepidum chlorosomes: A calculation of bacteriochlorophyll c per chlorosome and oligomer modeling. Biophysical Journal 2003, 85(4):2560-2565.
Bowen B, Woodbury N: Single-molecule fluorescence lifetime and anisotropy measurements of the red fluorescent protein, DsRed, in solution. Photochemistry and Photobiology 2003,77(4):362-369.
Bowen BP, Enderlein J, Woodbury NW: Single-molecule fluorescence spectroscopy of TOTO on poly-AT and poly-GC DNA. Photochemistry and Photobiology 2003, 78(6):576-581.
Bowen BP, Woodbury NW: TOTO binding affinity analysis using single-molecule fluorescence spectroscopy. Photochemistry and Photobiology 2003, 78(6):582-586.